Emmanuelle Querido

Single-particle track colocalization using CoPixie reveals the impact of cancer-associated POT1 mutations on telomerase-telomere interactions

The paper introduces CoPixie, a software for analyzing single-particle colocalization, and uses it to show cancer-associated POT1 mutations affect telomerase-telomere interactions.

Single-molecule imaging of telomerase RNA reveals a Recruitment-Retention model for telomere elongation

This study uses single-molecule imaging to reveal a Recruitment-Retention model for telomere elongation, showing how hTERT and TPP1 regulate hTR dynamics and how mutations affect telomere homeostasis.