Author

Mercedes Didier Garnham

Consejo Nacional de Investigaciones Científicas y TécnicasORCID 0000-0002-8059-0201Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Emir Salas‐SarduyiD· 2 shared Fernán AgüeroiD· 2 shared Fátima Agüero· 1 shared Juan Carlos Ramírez· 1 shared Lionel Urán LandaburuiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

5 top collaborators · 8 mutual co-author links

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2 shared papersMicrobiology

Emir Salas‐SarduyORCID

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2 papers

Recent·Most cited

Prioritization of chemical scaffolds using the TDR Targets database: an integrative workflow for Trypanosoma cruzi drug discovery

Lionel Urán Landaburu, Mercedes Didier Garnham, Emir Salas‐Sarduy, Fernán Agüero

This paper prioritizes chemical scaffolds for Trypanosoma cruzi drug discovery using the TDR Targets database, identifying 378 high-priority compounds and validating 7 with selective trypanocidal activity.

PLoS neglected tropical diseases · Aug 24, 2026Peer-reviewedMicrobiology

Identification of antifungal agents AR-12 and Fosmanogepix as anti-Trypanosoma cruzi drugs through an enhanced fluorogenic β-galactosidase phenotypic screening assay

Mercedes Didier Garnham, Fátima Agüero, Juan Carlos Ramírez, Fernán Agüero, Emir Salas‐Sarduy

This paper develops a fluorogenic β-galactosidase assay to screen antifungal compounds against Trypanosoma cruzi, identifying AR-12 and Fosmanogepix as potential drugs.

ACS Infectious Diseases · Jan 2, 2026Peer-reviewedMicrobiology