Author

Adrián Benito

Imperial College LondonORCID 0000-0002-8088-9537Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexandros SiskosiD· 1 shared Anke M. NijhuisiD· 1 shared Chandler Bray· 1 shared Chiharu WickremesingheiD· 1 shared Cristina Domingo BalcellsiD· 1 shared Edward W. TateiD· 1 shared Flora McKinneyiD· 1 shared Hector C. KeuniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alexandros SiskosORCID

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1 paper

Recent·Most cited

RAS/PI3K pathway mutations sensitise epithelial ovarian cancer cells to a PARP/NAMPT inhibitor combination

Michael Gruet, Yitao Xu, Lijie An, Yurui Ma, Cristina Domingo Balcells, Katie Tyson, Laila C. Evangelista, Sarah Spear, Yuewei Xu, Flora McKinney, Julia Babuta, Chandler Bray, Chiharu Wickremesinghe, Alexandros Siskos, Anke M. Nijhuis, , Hector C. Keun

This study identifies RAS/PI3K pathway mutations as a biomarker for sensitivity to PARP/NAMPT inhibitor combination therapy in epithelial ovarian cancer.

Communications Biology · Dec 19, 2025Peer-reviewedCancer Biology