Author

Julia Babuta

Imperial College LondonORCID 0000-0002-8034-1846Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Zoe HalliD· 2 shared Adrián BenitoiD· 1 shared Alexandros SiskosiD· 1 shared Alice E. KnaptoniD· 1 shared Alice P. SowtoniD· 1 shared Alicia JustiD· 1 shared Andrew J. MurrayiD· 1 shared Anke M. NijhuisiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersPhysiology

Zoe HallORCID

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Author profile →

3 papers

Recent·Most cited

Hepatic HIF2α modulates extra-hepatic disease-associated phenotypes during metabolic dysfunction-associated steatotic liver disease

Lorenz M.W. Holzner, Rosa M. Korpershoek, Youguo Niu, Anna Cochrane, Paula M. Darwin, Julia Babuta, Areesha Nazeer, Cecilia Castro, Alice P. Sowton, Alice E. Knapton, Benjamin D. Thackray, Julian Leether Griffin, Zoe Hall, Dino A. Giussani, Rob C. I. Wüst, Andrew J. Murray

This study investigates the role of hepatic HIF2α in MASLD, finding that its deletion leads to extra-hepatic complications like cardiac dysfunction and lean mass loss without protecting against liver disease progression.

bioRxiv · May 5, 2026 · PreprintPhysiology

RAS/PI3K pathway mutations sensitise epithelial ovarian cancer cells to a PARP/NAMPT inhibitor combination

Michael Gruet, Yitao Xu, Lijie An, Yurui Ma, Cristina Domingo Balcells, Katie Tyson, Laila C. Evangelista, Sarah Spear, Yuewei Xu, Flora McKinney, Julia Babuta, Chandler Bray, Chiharu Wickremesinghe, Alexandros Siskos, Anke M. Nijhuis, , Hector C. Keun

This study identifies RAS/PI3K pathway mutations as a biomarker for sensitivity to PARP/NAMPT inhibitor combination therapy in epithelial ovarian cancer.

Communications Biology · Dec 19, 2025Peer-reviewedCancer Biology

The Mycobacterium lipid transporter MmpL3 is dimeric in detergent solution, SMALPs and reconstituted nanodiscs

Sara Cioccolo, Joseph D. Barritt, Naomi L. Pollock, Zoe Hall, Julia Babuta, Pooja Sridhar, Alicia Just, Nina Morgner, Timothy R. Dafforn, Ian R. Gould, Bernadette Byrne

This paper shows MmpL3 from M. smegmatis forms dimers in various membrane mimetic systems, contradicting previous structural studies suggesting monomerism.

RSC Chemical Biology · Jan 1, 2024Peer-reviewedBiophysics