Epitranscriptomic editing of the RNA N6-methyladenosine modification by dCasRx conjugated methyltransferase and demethylase
Zhen Xia, Min Tang, Jiayan Ma, Hongyan Zhang, Ryan C Gimple, Briana C. Prager, Hongzhen Tang, Chongran Sun, Fuyi Liu, Peng Lin, Yutang Mei, Ruoxin Du, Jeremy N. Rich, Qi Xie
This study develops a dCasRx-based platform to edit m6A RNA modifications and demonstrates its use in studying m6A-binding protein functions.
Nucleic Acids Research · Jun 4, 2021Peer-reviewedMolecular Biology