Author

Jiayan Ma

Northwestern UniversityORCID 0000-0002-9286-3633Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Assay:GWAS summary statistics· 1

Frequent Co-Authors

Bartholomew Tam· 2 shared Jill P. MesiroviD· 2 shared Pablo TamayoiD· 2 shared William KimiD· 2 shared Alex Wenzel· 1 shared Amey Gupta· 1 shared Antony Castanza· 1 shared Briana C. PrageriD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersBioinformatics

Bartholomew Tam

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Author profile →

3 papers

Recent·Most cited

The Multi-scale Copula Index (MCI): a new information-theoretic measure of association and its applications in functional cancer genomics

Timothy Pham, Karina Meneses-Cime, Jiayan Ma, Bartholomew Tam, Amey Gupta, Michael R. Reich, Alex Wenzel, David Eby, Thorin T. Tabor, Helga Thorvaldsdóttir, Antony Castanza, Jill P. Mesirov, William Kim, Pablo Tamayo

The paper introduces the Multi-scale Copula Index (MCI), an information-theoretic measure of association, and demonstrates its utility in cancer genomics for capturing contextual associations in complex datasets.

bioRxiv · Oct 16, 2026 · PreprintBioinformatics

Deciphering the Functional Roles of Individual Cancer Alleles Across Comprehensive Cancer Genomic Studies

Jiayan Ma, Stephanie Ting, Bartholomew Tam, Timothy V. Pham, Michael M. Reich, Jill P. Mesirov, Pablo Tamayo, William Kim

This paper introduces REVEALER 2.0, an improved algorithm for identifying genomic alterations associated with functional profiles, showing increased speed and resolution for analyzing cancer genomic data.

bioRxiv · Nov 14, 2023 · PreprintBioinformatics

Epitranscriptomic editing of the RNA N6-methyladenosine modification by dCasRx conjugated methyltransferase and demethylase

Zhen Xia, Min Tang, Jiayan Ma, Hongyan Zhang, Ryan C Gimple, Briana C. Prager, Hongzhen Tang, Chongran Sun, Fuyi Liu, Peng Lin, Yutang Mei, Ruoxin Du, Jeremy N. Rich, Qi Xie

This study develops a dCasRx-based platform to edit m6A RNA modifications and demonstrates its use in studying m6A-binding protein functions.

Nucleic Acids Research · Jun 4, 2021Peer-reviewedMolecular Biology