Tsugumi Kawashima

The paper maps RNA-DNA interactions in 16 human cell types, showing cell-type-specific and dynamic networks that correlate with gene regulation and disease traits.

The paper introduces UNIChro-seq, a method for quantifying chromatin accessibility at target loci, and demonstrates its application in analyzing disease risk alleles and genome-edited variants.

CATaN integrates TF-GRNs and transcriptomes to identify genetic risk components across complex diseases, finding 588 significant CC components enriched for SNP heritability.

The paper identifies novel cell states and molecular profiles in lupus patients using single-cell data, linking them to disease severity and treatment outcomes.

This study maps transcription start sites and active enhancers in Galleria mellonella larvae during fungal infection and treatment using LQ-ssCAGE.

This paper introduces CFC-seq and SALA to sequence non-poly(A) RNAs, identifies 39,425 novel transcriptional units, and reveals a genomic code governing enhancer RNA fate based on promoter architecture.

The paper functionally annotates human long non-coding RNAs by systematically knocking down 285 lncRNAs and analyzing molecular phenotypes using CAGE sequencing.