Genetic & Genomic MedicineScientific ReportsPeer-reviewed
Polygenic prediction of human longevity on the supposition of pervasive pleiotropy
Mohammad Reza Jabalameli, Jhih-Rong Lin, Quanwei Zhang…·Zhengdong D. Zhang
This study develops a polygenic score to predict exceptional longevity by modeling pleiotropic genetic variants linked to aging-related traits, showing improved lifespan prediction and identifying potential drug targets.
3 citations