Intron retention as a new marker of the pre-disease state and its recovery to the normal state by a traditional Japanese multi-herbal medicine
Norihiro Okada, Kenshiro Oshima, Yuki Iwasaki, Akiko Maruko, Kenya Matsumura, Erica Iioka, Trieu-Duc Vu, Naoki Fujitsuka, Akinori Nishi, Aiko Sugiyama, Mitsue Nishiyama, Atsushi Kaneko, Kazushige Mizoguchi, Masahiro Yamamoto, Susumu Nishimura
The paper identifies intron retention as a marker of pre-disease and aging states and shows recovery by a traditional herbal medicine in klotho mice.
Gene · May 31, 2021Peer-reviewedMolecular Biology