A potential pathway that links intron retention with the physiological recovery by a Japanese herbal medicine
Norihiro Okada, Kenshiro Oshima, Akiko Maruko, Trieu-Duc Vu, Ming-Tzu Chiu, Mitsue Nishiyama, Masahiro Yamamoto, Akinori Nishi, Yoshinori Kobayashi
The paper investigates how Juzentaihoto (JTT) reduces intron retention in klotho mice by activating AMPK signaling, linking it to metabolic changes and physiological recovery.
bioRxiv · Dec 2, 2023 · PreprintBioinformatics