Author

Akiko Maruko

Kitasato University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Animal Behavior & Cognition· 1 Bioinformatics· 1 Genetic & Genomic Medicine· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 4 Approach:statistical model· 4 Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Organism:mouse· 2 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Approach:experimental assay· 1

Frequent Co-Authors

Kenshiro OshimaiD· 4 shared Norihiro OkadaiD· 4 shared Trieu-Duc VuiD· 3 shared Akinori NishiiD· 2 shared Ming-Tzu ChiuiD· 2 shared Mitsue NishiyamaiD· 2 shared Yoshinori KobayashiiD· 2 shared Aiko Sugiyama· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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4 shared papersAnimal Behavior & Cognition

Kenshiro OshimaORCID

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4 papers

Recent·Most cited

Asymmetric Neurogenomic States Emerge in Winners and Losers After Social Competition

Ming-Tzu Chiu, Trieu-Duc Vu, Akiko Maruko, Kenshiro Oshima, Hao‐Ven Wang, Norihiro Okada

The paper investigates how social competition affects neurogenomic states in Betta splendens, finding asymmetric transcriptomic network remodeling in winners and losers.

bioRxiv · Jul 29, 2026 · PreprintAnimal Behavior & Cognition

Intron retention can be an excellent marker for evaluating the depressed state and useful for discovering new pathways in the recovery of depression by a drug.

Norihiro Okada, Kenshiro Oshima, Akiko Maruko, Mariko Sekine, Naoki Ito, Akino Wakasugi, Eiko Mori, Hiroshi Odaguchi, Yoshinori Kobayashi

The paper identifies intron retention (IR) as a biomarker for depression and shows its utility in discovering recovery pathways through RNA-seq analysis of peripheral blood mononuclear cells.

Frontiers in Psychiatry · Sep 19, 2024Peer-reviewedGenetic & Genomic Medicine

A potential pathway that links intron retention with the physiological recovery by a Japanese herbal medicine

Norihiro Okada, Kenshiro Oshima, Akiko Maruko, Trieu-Duc Vu, Ming-Tzu Chiu, Mitsue Nishiyama, Masahiro Yamamoto, Akinori Nishi, Yoshinori Kobayashi

The paper investigates how Juzentaihoto (JTT) reduces intron retention in klotho mice by activating AMPK signaling, linking it to metabolic changes and physiological recovery.

bioRxiv · Dec 2, 2023 · PreprintBioinformatics

Intron retention as a new marker of the pre-disease state and its recovery to the normal state by a traditional Japanese multi-herbal medicine

Norihiro Okada, Kenshiro Oshima, Yuki Iwasaki, Akiko Maruko, Kenya Matsumura, Erica Iioka, Trieu-Duc Vu, Naoki Fujitsuka, Akinori Nishi, Aiko Sugiyama, Mitsue Nishiyama, Atsushi Kaneko, Kazushige Mizoguchi, Masahiro Yamamoto, Susumu Nishimura

The paper identifies intron retention as a marker of pre-disease and aging states and shows recovery by a traditional herbal medicine in klotho mice.

Gene · May 31, 2021Peer-reviewedMolecular Biology