Author

Chang‐Shi Chen

National Cheng Kung UniversityORCID 0000-0002-8201-3635Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 2

Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Approach:experimental assay· 2

Frequent Co-Authors

Chao-Wen WangiD· 1 shared Chih-Ling Liu· 1 shared Chiou‐Hwa YuhiD· 1 shared H.‐C. PengiD· 1 shared Horng‐Dar WangiD· 1 shared Jui-Ching WuiD· 1 shared Muniesh Muthaiyan ShanmugamiD· 1 shared Oliver Ingvar WagneriD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenetics

Chao-Wen WangORCID

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2 papers

Recent·Most cited

GeneticsGeneticsPeer-reviewedAug 31, 2026

Sperm-specific fertility factors SMZ-1/2 promote FB-MO biogenesis and MSP filament assembly in C. elegans

H.‐C. Peng, Chih-Ling Liu, Yi-Jhen Chiang…·Jui-Ching Wu

This study identifies SMZ-1/2 as PDZ proteins that initiate MSP filament assembly and FB-MO biogenesis in C. elegans sperm by coupling kinase signaling to organelle formation.

2 citationstop 3%

C. elegansexperimental assay

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GeneticsJournal of Biomedical SciencePeer-reviewedApr 27, 2026

Phosphatidylinositol Transfer Protein-1 Integrates Insulin/IGF-1 and TOR Signaling to Negatively Regulate Lifespan and Healthspan in Caenorhabditis elegans

Yen-Hung Lin, Yun-Hsun Liao, Sin-Bo Liao…·Horng‐Dar Wang

This study identifies pitp-1 as a regulator of healthy aging in C. elegans that integrates insulin/IGF-1 and TOR signaling to influence lifespan and healthspan.

DOI 10.1186/s12929-026-01246-x

C. elegansexperimental assay

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