Hua Dong

The paper benchmarks large language models for cell-type and gene set annotation using AnnDictionary, finding high accuracy in cell-type annotation and strong functional gene set recovery.

The paper uses spatial and single-cell transcriptomics to identify memory-specific transcriptional signatures in neurons and astrocytes of the basolateral amygdala, revealing their role in long-term memory formation.

This study identifies AATBC as a human-specific lncRNA that regulates adipocyte plasticity and mitochondrial function, linking it to metabolic health.