Inhibition of microglial GBA hampers the microglia-mediated anti-oxidant and protective response in neurons
Electra Brunialti, Alessandro Maria Villa, Marianna Mekhaeil, Federica Mornata, Elisabetta Vegeto, Adriana C. Maggi, Donato A. Di Monte, Paolo Ciana
This study shows that inhibiting microglial GBA reduces their ability to support neuronal antioxidant responses, increasing neuronal vulnerability to toxins.
Journal of Neuroinflammation · Sep 22, 2021Peer-reviewedNeuroscience