Author

Tija C. Jacob

University of PittsburghORCID 0000-0002-8288-7885Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell-cell communication· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Caitlyn A. ChapmaniD· 1 shared Jessica L. NuweriD· 1 shared Jon W. JohnsoniD· 1 shared Joshua M. Lorenz‐GuertiniD· 1 shared Matthew J. Bambino· 1 shared Nadya V. PovyshevaiD· 1 shared Sabyasachi Das· 1 shared Stephen D. MerineyiD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Caitlyn A. ChapmanORCID

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2 papers

Recent·Most cited

Chronic benzodiazepine treatment triggers gephyrin scaffold destabilization and GABAAR subsynaptic reorganization

Caitlyn A. Chapman, Nadya V. Povysheva, Tyler B. Tarr, Jessica L. Nuwer, Stephen D. Meriney, Jon W. Johnson, Tija C. Jacob

This study investigates how chronic benzodiazepine treatment affects gephyrin scaffold stability and GABAAR subsynaptic organization in neurons, revealing changes in synaptic structure and receptor distribution.

Frontiers in Cellular Neuroscience · Jul 4, 2025Peer-reviewedNeuroscience

Diazepam Accelerates GABAAR Synaptic Exchange and Alters Intracellular Trafficking

Joshua M. Lorenz‐Guertin, Matthew J. Bambino, Sabyasachi Das, Susan T. Weintraub, Tija C. Jacob

This study investigates how diazepam affects GABAAR synaptic exchange and intracellular trafficking, finding reduced gephyrin levels and altered receptor dynamics.

Frontiers in Cellular Neuroscience · Apr 26, 2019Peer-reviewedNeuroscience