Chronic benzodiazepine treatment triggers gephyrin scaffold destabilization and GABAAR subsynaptic reorganization
Caitlyn A. Chapman, Nadya V. Povysheva, Tyler B. Tarr, Jessica L. Nuwer, Stephen D. Meriney, Jon W. Johnson, Tija C. Jacob
This study investigates how chronic benzodiazepine treatment affects gephyrin scaffold stability and GABAAR subsynaptic organization in neurons, revealing changes in synaptic structure and receptor distribution.
Frontiers in Cellular Neuroscience · Jul 4, 2025Peer-reviewedNeuroscience