Author

Hsiao‐Yun Lin

Northwestern UniversityORCID 0000-0002-8295-4339Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:differential expression· 2 Assay:long-read sequencing· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Organism:human· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Cheng-Kai ShiauiD· 2 shared Lina LuiD· 2 shared Ruli GaoiD· 2 shared Timothy PaniD· 2 shared Eric L. Tong· 1 shared GaHyun LeeiD· 1 shared Jason T. HuseiD· 1 shared Jie YangiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBioinformatics

Cheng-Kai ShiauORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Fusion gene discovery in single cells from high throughput long read single cell transcriptomes

Cheng-Kai Shiau, Hsiao‐Yun Lin, Timothy Pan, Xiaodong Lü, Minhua Wang, Yueying He, Lina Lu, Jindan Yu, Ruli Gao

This paper introduces LongFUSE, a tool for detecting fusion genes in single-cell long-read RNA sequencing data, showing improved accuracy over existing methods.

bioRxiv · Jan 20, 2026 · PreprintBioinformatics

Delineating genotypes and phenotypes of individual cells from long-read single cell transcriptomes

Cheng-Kai Shiau, Lina Lu, Rachel E. Kieser, Kazutaka Fukumura, Timothy Pan, Hsiao‐Yun Lin, Jie Yang, Eric L. Tong, GaHyun Lee, Yuanqing Yan, Jason T. Huse, Ruli Gao

The paper introduces scNanoGPS, a toolkit for analyzing long-read single-cell transcriptomes to infer cell genotypes and phenotypes without short-read data, revealing cell-type-specific isoform and mutation patterns in tumors.

bioRxiv · Jan 24, 2023 · PreprintBioinformatics