Author

Mervin Meyer

University of the Western CapeORCID 0000-0002-8296-4860Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Organism:human· 1 Research Focus:variant effect prediction· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Adewale Oluwaseun FadakaiD· 1 shared Ashwil KleiniD· 1 shared David AdelekeiD· 1 shared Gomes Rahul· 1 shared Nicole Remaliah Samantha SibuyiiD· 1 shared Rick J. JanseniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperBioinformatics

Adewale Oluwaseun FadakaORCID

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1 paper

Recent·Most cited

BioinformaticsTranslational OncologyPeer-reviewedFeb 3, 2026

AlphaMissense pathogenicity scores predict response to immunotherapy and enhances the predictive capability of tumor mutation burden

David Adeleke, Adewale Oluwaseun Fadaka, Nicole Remaliah Samantha Sibuyi…·Rick J. Jansen

The paper introduces AlphaTMB, a composite biomarker combining tumor mutation burden with pathogenicity scores, showing improved survival prediction in immunotherapy response.

DOI 10.1016/j.tranon.2026.102697

humanwhole-exome sequencing