Author

Evilin Naname Komegae

Universidade de São PauloORCID 0000-0002-8299-6010Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:rat· 1

Frequent Co-Authors

Alexandre A. SteineriD· 1 shared Camila F. BritoiD· 1 shared Eduardo Hermógenes MorettiiD· 1 shared Elizabeth Alexandra FlatowiD· 1 shared Isis Ferraz Libório Trzan· 1 shared Jady T. GuedesiD· 1 shared Lucas Maciel Mauriz MarquesiD· 1 shared Monique T. FonsecaiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperPhysiology

Alexandre A. SteinerORCID

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1 paper

Recent·Most cited

Spleen-dependent role of cyclooxygenase-1 in the physiological manifestations of severity in systemic inflammation

Camila F. Brito, Eduardo Hermógenes Moretti, Isis Ferraz Libório Trzan, Monique T. Fonseca, Lucas Maciel Mauriz Marques, Jady T. Guedes, Evilin Naname Komegae, Elizabeth Alexandra Flatow, Norberto P. Lopes, Alexandre A. Steiner

This study shows that COX-1 in the spleen mediates systemic inflammation severity through PGE2 and PGD2, as SC-560's effect on LPS-induced symptoms is lost after splenectomy.

bioRxiv · Jul 11, 2026 · PreprintPhysiology