Label-Free Multimodal Volumetric Imaging of Colon Cancer Tissue via Registration of Propagation-Based Phase-Contrast CT, Light-Sheet, and Three-Photon Microscopy
Christian Dullin, Matthias Schroeter, Diana Pinkert‐Leetsch, Fernanda Ramos‐Gomes, M. Andrea Markus, Jeannine Missbach‐Guentner, Hanibal Bohnenberger, Philipp Ströbel, Frauke Alves
This paper develops a registration pipeline to align multimodal 3D imaging data from colon cancer tissue and uses unsupervised clustering to identify spatially coherent tissue regions.
bioRxiv · May 25, 2026 · PreprintPathology