Frauke Alves

Label-Free Multimodal Volumetric Imaging of Colon Cancer Tissue via Registration of Propagation-Based Phase-Contrast CT, Light-Sheet, and Three-Photon Microscopy

This paper develops a registration pipeline to align multimodal 3D imaging data from colon cancer tissue and uses unsupervised clustering to identify spatially coherent tissue regions.

Natural aging drives a subclinical cardiovascular phenotype in a non-human primate

This study examines natural cardiovascular aging in non-human primates, finding histological and molecular changes associated with aging, including fibrosis, inflammation, and atherosclerosis.

Exploring Ventilator-Induced Lung Injury: A Comprehensive Ex-Vivo Study Using Phase-Contrast MicroCT and Atomic Force Microscopy

This study investigates ventilator-induced lung injury in a rat model using ex-vivo imaging and mechanical analysis, finding that fibrotic lungs show reduced airspace enlargement compared to healthy lungs after injurious ventilation.

Demonstrating Soft X-Ray Tomography in the lab for correlative cryogenic biological imaging using X-rays and light microscopy

The paper demonstrates the SXT-100, a compact soft X-ray microscope, for correlative cryogenic biological imaging with high resolution and minimal sample damage.

Autonomous bioluminescence emission from transgenic mice

This paper generates a transgenic mouse line that autonomously emits bioluminescence in vivo without requiring exogenous substrates.