E3 ubiquitin ligase Deltex facilitates the expansion of Wingless gradient and antagonizes Wingless signaling through a conserved mechanism of transcriptional effector Armadillo/β-catenin degradation
Vartika Sharma, Nalani Sachan, Bappi Sarkar, Mousumi Mutsuddi, Ashim Mukherjee
This study identifies Deltex as a regulator of Wg signaling by modulating the gradient and degradation of Armadillo/β-catenin across species.
eLife · Jun 20, 2024Peer-reviewedDevelopmental Biology