Disruption of Fuz in mouse embryos generates hypoplastic hindbrain development and reduced cranial nerve ganglia.
Carlo Donato Caiaffa, Yogeshwari Sanjayrao Ambekar, Manmohan Singh, Ying Linda Lin, Bogdan J. Wlodarczyk, Salavat R. Aglyamov, Giuliano Scarcelli, Kirill V. Larin, Richard H. Finnell
This paper shows that disrupting Fuz in mouse embryos causes hypoplastic hindbrain development and reduced cranial nerve ganglia due to defective cilia formation and impaired Sonic Hedgehog signaling.
Developmental Dynamics · Mar 19, 2024Peer-reviewedDevelopmental Biology