Author

Roman Popov

Karlsruhe Institute of TechnologyORCID 0000-0002-8400-0678Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:protein sequence· 1

Frequent Co-Authors

Alexander Nesterov‐MuelleriD· 3 shared Alex DuloviciD· 2 shared Clemens von Bojničić‐KninskiiD· 2 shared Dimitry SchmidtiD· 2 shared Hubert S. BernaueriD· 2 shared Johanna GriesbaumiD· 2 shared Josef M. MaieriD· 2 shared Nathalie BiniaminoviD· 2 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

Alexander Nesterov‐MuellerORCID

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3 papers

Recent·Most cited

Dual-Layer Serological Encoding: Integrating Pathogen-Derived and Host-Reactive Peptide Signatures Reveals Complementary Dimensions of HIV Immune Response

Dimitry Schmidt, Sergey Biniaminov, Nathalie Biniaminov, Clemens von Bojničić‐Kninski, Roman Popov, Josef M. Maier, Hubert S. Bernauer, Johanna Griesbaum, Nicole Schneiderhan‐Marra, Alex Dulovic, Alexander Nesterov‐Mueller

The paper evaluates a dual-layer serological framework using HIV-derived and host-derived peptides to improve diagnostic accuracy and reveal immune state changes in HIV-positive individuals.

bioRxiv · Apr 22, 2026 · PreprintImmunology

High-density peptide arrays detect tuberculosis through immune remodeling, not only antigen recognition alone

Dimitry Schmidt, Sergey Biniaminov, Nathalie Biniaminov, Clemens von Bojničić‐Kninski, Roman Popov, Josef M. Maier, Hubert S. Bernauer, Johanna Griesbaum, Nicole Schneiderhan‐Marra, Alex Dulovic, Alexander Nesterov‐Mueller

The paper uses high-density peptide arrays to detect tuberculosis by analyzing immune repertoire remodeling rather than antigen-specific recognition, achieving high accuracy in HIV-negative individuals.

bioRxiv · Apr 20, 2026 · PreprintImmunology

Substitutional landscape of a split fluorescent protein fragment

Oana N. Antonescu, Andreas Rasmussen, Nicole A. M. Damm, Ditte F. Heidemann, Roman Popov, Alexander Nesterov‐Mueller, Kristoffer E. Johansson, Jakob Rahr Winther

The paper screens split fluorescent protein variants to identify substitutions that enhance binding affinity.

bioRxiv · May 20, 2020 · PreprintSynthetic Biology