Author

Kristen A. Baltgalvis

Vividion Therapeutics (United States)ORCID 0000-0002-8405-9493Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Brian E. NordiniD· 1 shared David S. WeinsteiniD· 1 shared Gabriel M. SimoniD· 1 shared Jeffery W. KellyiD· 1 shared Kent T. Symons· 1 shared Matthew P. PatricelliiD· 1 shared Zeba RizviiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Brian E. NordinORCID

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintOct 15, 2026

Allosteric covalent inhibition of cereblon through cryptic cysteine targeting

Zeba Rizvi, Brian E. Nordin, Kent T. Symons…·Jeffery W. Kelly

The paper identifies covalent ligands targeting a cryptic cysteine in CRBN, demonstrating their ability to inhibit neosubstrate degradation by trapping CRBN in an inactive conformation.

DOI 10.64898/2026.10.10.758245

humanproteomics

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