Author

Xianjun Chen

East China University of Science and TechnologyORCID 0000-0002-8475-332XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Evolutionary Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:large language model· 1 Research Focus:protein design· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Bibi ZhangiD· 1 shared Chenxin Cao· 1 shared Fangting ZuoiD· 1 shared Huiwen LiiD· 1 shared Jack X. Chen· 1 shared L C ZhuiD· 1 shared Lu JiangiD· 1 shared Mengyue Fang· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperEvolutionary Biology

Bibi ZhangORCID

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2 papers

Recent·Most cited

A superfolding sfPepper enables superresolution and single-molecule RNA imaging in live cells

Xin Jiang, Huiwen Li, Lu Jiang, Chenxin Cao, Qi Jiang, Ni Su, Mengyue Fang, Zhengda Chen, Fangting Zuo, Yuzheng Zhao, Xiwei Tian, Xianjun Chen, L C Zhu, Yi An Yang

This paper introduces sfPepper, a superfolder RNA aptamer that improves folding efficiency, brightness, and imaging capabilities for live-cell RNA visualization.

bioRxiv · Jul 16, 2026 · PreprintMolecular Biology

Capturing Natural Evolution in Function-guided RNA Design via Genomic Foundation Models

Yanjie Huang, Bibi Zhang, Jack X. Chen, Runze Ma, Zhongyue Zhang, Xianjun Chen, Yi Yang, Shuangjia Zheng

The paper introduces a zero-shot RNA design method using genomic foundation models, achieving improved fluorescence and binding affinity in RNA aptamers.

bioRxiv · Apr 8, 2025 · PreprintEvolutionary Biology