N1-methylpseudouridine-incorporated mRNA enhances exogenous protein expression and suppresses immunogenicity in primary human fibroblast-like synoviocytes
Sho Mokuda, Hirofumi Watanabe, Hiroki Kohno, Michinori Ishitoku, Kei Araki, Shintaro Hirata, Eiji Sugiyama
This study shows that N1-methylpseudouridine-modified mRNA increases protein expression and reduces immunogenicity in human fibroblast-like synoviocytes.
Cytotechnology · Jun 30, 2022Peer-reviewedMolecular Biology