Author

Hirofumi Watanabe

Hiroshima University HospitalORCID 0000-0003-0657-5385Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Molecular Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Organism:human· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Baylee C. WestburyiD· 1 shared Chihiro Sakurazawa· 1 shared Eiji SugiyamaiD· 1 shared Ge TaoiD· 1 shared Glenn I. FishmaniD· 1 shared Henry M. SucoviD· 1 shared Hiroki KohnoiD· 1 shared Ichiei NaritaiD· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperDevelopmental Biology

Baylee C. WestburyORCID

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3 papers

Recent·Most cited

PhysiologybioRxivPreprintJul 24, 2026

Natriuretic Peptide Augmentation Attenuates Renin Cell Hyperactivation and Afferent Arteriolar Hypertrophy During Long-Term Renin-Angiotensin System Inhibition

Tomomi Shiiya, Hirofumi Watanabe, Ryo Aida…·Suguru Yamamoto

This study shows that augmenting natriuretic peptide signaling with ARNI reduces renin cell activation and afferent arteriolar hypertrophy during RAS inhibition, preserving therapeutic benefits.

DOI 10.64898/2026.07.21.739692

mousebulk RNA-seq

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Developmental BiologybioRxivPreprintOct 29, 2022

Purkinje cardiomyocytes of the ventricular conduction system are highly diploid but not regenerative

Hirofumi Watanabe, Ge Tao, Peiheng Gan…·Henry M. Sucov

The paper identifies Purkinje cardiomyocytes as a diploid subpopulation in the ventricular conduction system that lacks regenerative capacity despite their diploid status.

DOI 10.1101/2022.10.29.514354

mousebulk RNA-seq

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Molecular BiologyCytotechnologyPeer-reviewedJun 30, 2022

N1-methylpseudouridine-incorporated mRNA enhances exogenous protein expression and suppresses immunogenicity in primary human fibroblast-like synoviocytes

Sho Mokuda, Hirofumi Watanabe, Hiroki Kohno…·Eiji Sugiyama

This study shows that N1-methylpseudouridine-modified mRNA increases protein expression and reduces immunogenicity in human fibroblast-like synoviocytes.

17 citations

humanbulk RNA-seq

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