Felix von Stetten

This paper introduces a sample preparation workflow (SP3) that enables nanopore-based protein identification by decoupling proteolysis from interfering components, demonstrating its effectiveness with tryptic digests of myelin basic protein.

The paper introduces PICO, a novel immunoassay for absolute quantification of proteoforms, validated with recombinant and non-recombinant targets and demonstrating combinatorial multiplexing capabilities.

The paper validates scRNA-seq results using scRT-ddPCR, demonstrating improved detection of low-abundant transcripts like ErbB2 in MCF7 cells.