Identification and Characterization of Adult Islet Pancridia Cells Capable of Differentiating into Islet Organoids
Carly M. Darden, Jayachandra Kuncha, Jeffrey T. Kirkland, JORDAN D. MATTKE, Srividya Vasu, Bashoo Naziruddin, Michael C. Lawrence
The paper identifies and characterizes islet pancridia cells (IPCs) from the adult pancreas that can differentiate into islet organoids, revealing calcium-dependent and epigenetic mechanisms involved in this process.
bioRxiv · Jul 28, 2025 · PreprintDevelopmental Biology