Author

Matthias Christian Kugler

New York UniversityORCID 0000-0002-8587-6129Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:metagenomics· 1

Frequent Co-Authors

Leopoldo N. SegaliD· 2 shared Yonghua LiiD· 2 shared Afshana HoqueiD· 1 shared Alena LukovnikovaiD· 1 shared Alexander Czachor· 1 shared Alma SolisiD· 1 shared Amelia RoselliiD· 1 shared Amy Gilmour· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

Leopoldo N. SegalORCID

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2 papers

Recent·Most cited

Toll-Like-Receptor 5 protects against pulmonary fibrosis by reducing lung dysbiosis

Yosuke Sakamachi, Emma Wiley, Carol S. Trempus, Harrison Jacobs, Alma Solis, Collin G. Johnson, Xianglin Meng, Salik Hussain, Amelia Roselli, Jay H. Lipinski, David N. O’Dwyer, Thomas A. Randall, Jason Malphurs, Brian N. Papas, B. G. Wu, , Stavros Garantziotis

TLR5 deficiency is linked to pulmonary fibrosis due to its role in preventing microbial dysbiosis following lung injury.

Science Translational Medicine · Jun 3, 2026Peer-reviewedImmunology

Lower Airway Dysbiosis in NTM+ Bronchiectasis is Associated with NET-Predominant Severe Phenotypes

S. Singh, Fares Darawshy, Kirby Erlandson, Jayanth Kumar Narayana, Qingsheng Li, Yonghua Li, I. Atandi, Kelsey Krolikowski, Shrey Patel, Destiny Collazo, Micheál Mac Aogáin, Amy Gilmour, Merete Bridget Long, Miao Chang, Afshana Hoque, , Leopoldo N. Segal

This study links lower airway microbiota and neutrophilic inflammation in NTM+ bronchiectasis to severe disease phenotypes through network analysis and preclinical models.

American Journal of Respiratory and Critical Care Medicine · Jan 30, 2026Peer-reviewedImmunology