Author

Leopoldo N. Segal

New York UniversityORCID 0000-0003-3559-9431Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Bioinformatics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Organism:human· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:metagenomics· 2 Organism:mouse· 2 Approach:statistical model· 2

Frequent Co-Authors

Yonghua LiiD· 4 shared Imran SulaimaniD· 3 shared Benjamin G. WuiD· 2 shared Jun-Chieh James TsayiD· 2 shared Matthias Christian KugleriD· 2 shared Adriana HeguyiD· 1 shared Afshana HoqueiD· 1 shared Alena LukovnikovaiD· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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4 shared papersImmunology

Yonghua LiORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

ImmunologyScience Translational MedicinePeer-reviewedJun 3, 2026

Toll-Like-Receptor 5 protects against pulmonary fibrosis by reducing lung dysbiosis

Yosuke Sakamachi, Emma Wiley, Carol S. Trempus…·Stavros Garantziotis

TLR5 deficiency is linked to pulmonary fibrosis due to its role in preventing microbial dysbiosis following lung injury.

4 citationstop 3%

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ImmunologyAmerican Journal of Respiratory and Critical Care MedicinePeer-reviewedJan 30, 2026

Lower Airway Dysbiosis in NTM+ Bronchiectasis is Associated with NET-Predominant Severe Phenotypes

S. Singh, Fares Darawshy, Kirby Erlandson…·Leopoldo N. Segal

This study links lower airway microbiota and neutrophilic inflammation in NTM+ bronchiectasis to severe disease phenotypes through network analysis and preclinical models.

4 citationstop 1%

mousebulk RNA-seq

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BioinformaticsNature CommunicationsPeer-reviewedNov 8, 2023

Inflammation in the tumor-adjacent lung as a predictor of clinical outcome in lung adenocarcinoma

Igor Dolgalev, Hua Zhou, Nina Murrell…·Aristotelis Tsirigos

This study identifies inflammation in tumor-adjacent lung tissue as a predictor of clinical outcome in lung adenocarcinoma using multi-omic analysis of 143 stage I cases.

37 citationstop 4%

humanbulk RNA-seq

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Molecular BiologybioRxivPreprintJun 16, 2022

More than Mycobacterium tuberculosis: specific site-of-disease microbial communities, functional capacities, and their distinct clinical profiles in tuberculous lymphadenitis

Georgina R. Nyawo, Charissa Camille. Naidoo, Benjamin G. Wu…·Grant Theron

The paper identifies distinct microbial community clusters in tuberculosis lymphadenitis linked to clinical features and immune responses.

1 citation

humanmetagenomics

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