Author

Bruna Rodrigues Cardoso Miranda

Universidade Federal do Rio de JaneiroORCID 0000-0002-8588-062XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Alana S O Souza· 1 shared Carla Verissimo· 1 shared Helena L. BorgesiD· 1 shared João Marcos de Azevedo DelouiD· 1 shared Julia S. M. ConceiçãoiD· 1 shared Letícia Silva FerraziD· 1 shared Martín BonaminoiD· 1 shared Mayra CarneiroiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

Alana S O Souza

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1 paper

Recent·Most cited

CDK4/6 inhibitors enhance oxaliplatin efficacy in colorectal cancer with RB-dependent and tumor-selective activity in intestinal model

Alana S O Souza, Julia S. M. Conceição, Letícia Silva Ferraz, João Marcos de Azevedo Delou, Bruna Rodrigues Cardoso Miranda, Carla Verissimo, Mayra Carneiro, Stevens Kastrup Rehen, Martín Bonamino, Helena L. Borges

This study shows CDK4/6 inhibitors synergize with oxaliplatin in colorectal cancer, with RB-dependent tumor-selective activity and preserved efficacy at low inhibitor doses.

bioRxiv · Apr 19, 2026 · PreprintCancer Biology