Determinants of ligand-functionalized DNA nanostructure-cell interactions
Glenn A. O. Cremers, Bas J. H. M. Rosier, Ab Meijs, Nicholas B. Tito, Sander M. J. van Duijnhoven, Hans van Eenennaam, Lorenzo Albertazzi, Tom F. A. de Greef
This study investigates how design parameters affect the binding of antibody-functionalized DNA nanostructures to cell surface receptors, finding that nanostructure size and DNA handle location influence receptor binding.
Journal of the American Chemical Society · Jun 28, 2021Peer-reviewedSynthetic Biology