Developmental BiologybioRxivPreprint
Increased tissue tension caused by depletion of CLDN3 in the non-neural ectoderm causes neural fold fusion defects in chick embryos
Elizabeth-Ann Legere, Marie Dumont, Yojiro Yamanaka…·Aimee K. Ryan
This study shows that CLDN3 depletion in chick embryos increases tissue tension, leading to neural fold fusion defects in the spinal region by altering apical cytoskeletal dynamics.
DOI 10.1101/2025.10.14.682463