Moritz Smolka

Sniffles2 improves SV detection accuracy and speed, enabling mosaic and population-level SV calling with applications in neurological disorders.

The paper analyzes sensory cell types in Platynereis dumerilii to explore the evolutionary relationship between photo- and mechanoreceptors, finding that r-Opsin1 modulates mechanosensation through light-dependent mechanisms.

The paper introduces open-source tools for detecting structural variations using long-read sequencing, achieving high sensitivity and precision in complex regions and identifying novel variants in human genomes.

Teaser benchmarks and optimizes read mapping parameters for NGS data, showing how Bowtie2 can be tailored for different datasets.