Carlo Manzo

ExoFILT uses transfer learning to automate exocytic event detection in single-particle tracking data, improving speed and consistency.

The paper uses multimodal imaging to study the dynamic structure of the exocyst complex during exocytosis, revealing its conformational changes and tethering mechanism.

The paper develops a Bayesian method using Gaussian Processes to map diffusion coefficients continuously across membranes from particle trajectories without data binning.