3D live imaging and phenotyping of the subcellular cytotoxicity in cancer immunotherapy using event-triggered Bessel oblique plane microscopy
Zhaofei Wang, Jie Wang, Yuxuan Zhao, Jin Jin, Wentian Si, Longbiao Chen, Man Zhang, Yao Zhou, Shiqi Mao, Yicheng Zhang, Yicheng Zhang, Liting Chen, Peng Fei
This study uses EBOPM to analyze subcellular events in CAR-T cells during immunotherapy, identifying key parameters correlated with cytotoxic function.
Nature Communications · Aug 6, 2024Peer-reviewedImmunology