Author

Wai Soon Chan

National Institutes for Quantum Science and TechnologyORCID 0000-0002-8666-8778Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:clustering· 1 Approach:graph neural network· 1 Assay:Hi-C· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Chi-Hong Chang Chien· 1 shared Christopher Llynard D. OrtiziD· 1 shared Hidetoshi KonoiD· 1 shared Jinhao ZouiD· 1 shared Lee‐Wei YangiD· 1 shared Rong‐Long Pan· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 10 mutual co-author links

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1 shared paperBioinformatics

Chi-Hong Chang Chien

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2 papers

Recent·Most cited

HiC-SCA: A Spectral Clustering Method for Reliable A/B Compartment Assignment From Hi-C Data

Wai Soon Chan, Hidetoshi Kono

HiC-SCA improves A/B compartment assignment from Hi-C data through spectral clustering with noise filtering and resolution selection, showing better consistency across datasets.

bioRxiv · Sep 22, 2025 · PreprintGenomics

DR-SIP: Protocols for Higher Order Structure Modeling with Distance Restraints- and Cyclic Symmetry-Imposed Packing

Wai Soon Chan, Jinhao Zou, Christopher Llynard D. Ortiz, Chi-Hong Chang Chien, Rong‐Long Pan, Lee‐Wei Yang

The paper introduces two filters, DR and SIP, to improve quaternary structure prediction for transmembrane proteins using distance restraints and cyclic symmetry.

Bioinformatics · Jul 24, 2019Peer-reviewedBioinformatics