Author

Seithikurippu Ratnas Pandi-Perumal

Chandigarh UniversityORCID 0000-0002-8686-7259Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Approach:statistical model· 4 Research Focus:phylogenetics / evolution· 2 Organism:E. coli· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1

Frequent Co-Authors

D. Warren SpenceiD· 4 shared Konda Mani SaravananiD· 4 shared Saravana Babu ChidambaramiD· 4 shared Sayan PauliD· 4 shared Ganesh N. PandianiD· 1 shared George C. Abraham· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 14 mutual co-author links

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4 shared papersGenomics

D. Warren SpenceORCID

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4 papers

Recent·Most cited

Examining Sleep Signals at the Cradle of Life: Can phylogenomic analysis of the Last Universal Common Ancestor (LUCA) reveal the fundamental role of sleep?

Seithikurippu Ratnas Pandi-Perumal, Konda Mani Saravanan, D. Warren Spence, Sayan Paul, Ganesh N. Pandian, Saravana Babu Chidambaram

This paper uses phylogenomic analysis to examine sleep-related genes in LUCA, finding conserved genes linked to signaling, metabolism, and circadian rhythms, suggesting their fundamental role in evolution.

Molecular Genetics and Genomics · Jan 6, 2026Peer-reviewedGenomics

Studying sleep orthologs in Epsilonproteobacteria through an evolutionary lens: Investigating sleep mysteries through phylogenomics

Seithikurippu Ratnas Pandi-Perumal, Konda Mani Saravanan, Sayan Paul, D. Warren Spence, Saravana Babu Chidambaram

The paper uses phylogenomic methods to study sleep-related gene orthologs in Epsilonproteobacteria, identifying conserved proteins and their functional adaptations.

World Journal of Microbiology and Biotechnology · Apr 27, 2025Peer-reviewedGenomics

Unraveling the Mysteries of Sleep: Exploring Phylogenomic Sleep Signals in the Recently Characterized Archaeal Phylum Lokiarchaeota near Loki's Castle

Seithikurippu Ratnas Pandi-Perumal, Konda Mani Saravanan, Sayan Paul, D. Warren Spence, Saravana Babu Chidambaram

This paper uses phylogenomics to identify sleep-related genes in Lokiarchaeota, suggesting a conserved role for sleep in cellular maintenance and organismal fitness.

International Journal of Molecular Sciences · Dec 25, 2024Peer-reviewedBioinformatics

Cross-Kingdom Genomic Conservation of Human Sleep-Related Gene Orthologs: Phylogenomic Evidence from Chlamydomonas reinhardtii

Seithikurippu Ratnas Pandi-Perumal, Konda Mani Saravanan, Sayan Paul, George C. Abraham, D. Warren Spence, Saravana Babu Chidambaram

This study identifies conserved sleep-related gene orthologs in Chlamydomonas reinhardtii, suggesting evolutionary continuity of sleep functions across species.

bioRxiv · Nov 2, 2024 · PreprintBioinformatics