Marco Vanoni

The paper develops an E. coli strain for enhanced threonine production using metabolic modeling and experiments, and explores its application for producing high-value chemicals like 2,5-dimethylpyrazine.

This study uses a computational framework to analyze non-canonical TCA cycle activity in cancer cell lines, linking it to Warburg metabolism and cancer hallmarks.

The paper develops a multiscale computational model integrating metabolism, growth, and cell cycle in yeast to predict that fermentation modulates cell size under different growth conditions.

INTEGRATE integrates metabolomics and transcriptomics data to identify metabolic flux regulation at the enzyme expression and metabolic levels in cancer cell lines.

This paper integrates single-cell RNA-seq data into metabolic models to characterize tumour cell populations and identifies metabolic heterogeneity and interactions.