Atomic elementary flux modes explain the steady state flow of metabolites in large-scale flux networks
Justin G. Chitpin, Theodore J. Perkins
The paper introduces atomic elementary flux modes (AEFMs) to efficiently analyze metabolic fluxes in large networks, showing they outperform traditional EFMs and reveal new insights into carbon and nitrogen metabolism in HepG2 cells.
Cell Reports Methods · May 22, 2026Peer-reviewedBioinformatics