Author

Irina Alecu

University Hospital ZurichORCID 0000-0002-7659-9190Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:metabolomics· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Adam Majcher· 1 shared Andreas J. HülsmeieriD· 1 shared Angela M. CrawleyiD· 1 shared Anuradha SurendraiD· 1 shared Christoph ArenziD· 1 shared Elkhan YusifoviD· 1 shared Essa M. SaiediD· 1 shared Graeme P. Taylor· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBiochemistry

Adam Majcher

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2 papers

Recent·Most cited

CYP4F2-mediated ω-hydroxylation of 1-deoxysphingolipids reveals a new hepatic detoxification pathway

Adam Majcher, Essa M. Saied, Zoltán Kutalik, Maftuna Shamshiddinova, Andreas J. Hülsmeier, Par Bjorklund, Elkhan Yusifov, Irina Alecu, Christoph Arenz, Thorsten Hornemann

This study identifies CYP4F2 as a key enzyme mediating ω-hydroxylation of 1-deoxySLs, revealing a new hepatic detoxification pathway that reduces their cytotoxicity.

bioRxiv · May 14, 2026 · PreprintBiochemistry

BATL: Bayesian annotations for targeted lipidomics

Justin G. Chitpin, Anuradha Surendra, Thao Nguyen-Tran, Graeme P. Taylor, Hongbin Xu, Irina Alecu, Roberto Ortega, Julianna J. Tomlinson, Angela M. Crawley, Michaeline McGuinty, Michael G. Schlossmacher, Rachel J. Saunders-Pullman, Miroslava Čuperlović‐Culf, Steffany A. L. Bennett, Theodore J. Perkins

BATL is a Bayesian classifier for targeted lipidomics that annotates LC-ESI-MS/MS peaks with high accuracy using eight features, achieving over 95% correct identification in SRM datasets.

Bioinformatics · Dec 21, 2021Peer-reviewedBioinformatics