Angela M. Crawley

Characterizing postoperative T and B cell dysfunction in cancer surgery patients, using COVID-19 as a model antigen

This study examines how cancer surgery affects T and B cell responses to a model antigen, showing reduced cytokine-producing CD8+ T cells and antibody-secreting B cells post-surgery.

CYP1A1/1A2 enzymes mediate glucose homeostasis and insulin secretion in mice in a sex-specific manner

This study shows that CYP1A1/1A2 enzymes affect glucose homeostasis and insulin secretion in mice, with sex-specific differences in their impact on metabolic responses to high-fat diets.

BATL: Bayesian annotations for targeted lipidomics

BATL is a Bayesian classifier for targeted lipidomics that annotates LC-ESI-MS/MS peaks with high accuracy using eight features, achieving over 95% correct identification in SRM datasets.