Author

Paul J. Gallins

North Carolina State UniversityORCID 0000-0002-8707-8841Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Organism:human· 1 Research Focus:imputation· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Fred A. WrightiD· 2 shared Yi‐Hui ZhouiD· 2 shared Elizabeth BlueiD· 1 shared Elizabeth Pugh· 1 shared Garry R. CuttingiD· 1 shared Harriet CorvoliD· 1 shared Hong DangiD· 1 shared Hua LingiD· 1 shared

Activity by Year

2019-2022 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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2 shared papersGenetics

Fred A. WrightORCID

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2 papers

Recent·Most cited

GeneticsHuman Genetics and Genomics AdvancesPeer-reviewedJan 11, 2022

Leveraging TOPMed Imputation Server and Constructing a Cohort-Specific Imputation Reference Panel to Enhance Genotype Imputation among Cystic Fibrosis Patients

Quan Sun, Weifang Liu, Jonathan D. Rosen…·Yun Li

The paper improves genotype imputation for CF patients using the TOPMed reference panel and a CF-specific imputation panel, enhancing marker coverage and PRS accuracy.

23 citations

humanwhole-genome sequencing

𝕏 PostBluesky

BioinformaticsbioRxivPreprintNov 9, 2019

Marker-Trait Complete Analysis

Yi‐Hui Zhou, Paul J. Gallins, Fred A. Wright

The paper introduces MTCA, a method for accurate statistical testing of trait-genomic feature associations, handling maxima and sums of r2 statistics while accounting for correlations.

DOI 10.1101/836494

GWAS summary statisticsstatistical model

𝕏 PostBluesky