Marek S. Wiewiórka

polars-bio - fast, scalable and out-of-core operations on large genomic interval datasets

polars-bio provides fast, scalable, and out-of-core operations for genomic interval datasets, outperforming existing libraries in speed and memory efficiency.

Cloud-native distributed genomic pileup operations

The paper presents a distributed pileup algorithm for genomic analysis that improves speed and memory efficiency in cloud environments.

SeQuiLa-cov: A fast and scalable library for depth of coverage calculations

SeQuiLa-cov provides a fast and scalable tool for depth of coverage calculations, achieving over 100x speedup compared to existing methods.

Clustering-based optimization method of reference set selection for improved CNV callers performance

This paper evaluates reference set selection methods for CNV callers using WES data and finds that clustering-based approaches improve detection performance and efficiency.