Molecular BiologyCell DiscoveryPeer-reviewed
Structural and molecular basis of the epistasis effect in enhanced affinity between SARS-CoV-2 KP.3 and ACE2
Leilei Feng, Zhaoxi Sun, Yuchen Zhang…·Yunlong Cao
This study investigates the structural and molecular basis of enhanced ACE2 binding in SARS-CoV-2 KP.3 variant through Cryo-EM and MD simulations, revealing synergistic mutational effects.
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