Identity, ontogeny, and age-related changes in splenic white pulp macrophages in mouse and human spleen
Kalyn R. Thayer, Maxwell J. Schleck, Yuliana V. Sokolenko, Radmila A. Nafikova, Zhan Yu, Z. Lu, Karolina J. Senkow, Elsie G. Bunyan, William T. Plodzeen, Constance E. Runyan, Rogan A. Grant, Suchitra Swaminathan, Duc Thi Hong Phan, Hiam Abdala‐Valencia, Chitaru Kurihara, , Alexander V. Misharin
This study identifies and characterizes splenic macrophage subsets in mouse and human, revealing their ontogeny, dynamics, and age-related changes.
bioRxiv · Apr 6, 2026 · PreprintImmunology