Modelling ferroptosis in a human microglial line by sequential exposure to iron and GPX4 inhibition
Renaud Bussiere, Nikhil Kumar Tulsian, Cecilia Wieder, Dewi Mcconnaughie, Evie Tynan, Andrew Lowe, Esther Cheow, Matthew Choo, Jill C. Richardson, James A. Duce, Sébastien Gillotin
The paper establishes a human microglial ferroptosis model using HMC3 cells and identifies dysregulated lipid species and metabolic pathways associated with ferroptosis.
Oxidative Medicine and Cellular Longevity · Jan 1, 2026Peer-reviewedNeuroscience