Sébastien Gillotin

The paper establishes a human microglial ferroptosis model using HMC3 cells and identifies dysregulated lipid species and metabolic pathways associated with ferroptosis.

This study shows that inhibiting LSD1, a histone demethylase, restores learning and memory in aged mice by reversing age-related defects in H3K4me3 dynamics and synaptic plasticity.

This paper uses mass spectrometry to identify age- and activity-dependent changes in histone post-translational modifications in mouse hippocampi, proposing a framework for integrating these findings into ageing research.